HPE P50444-B21 16GB DDR5-4800 ECC Registered Memory Kit

Overview

The HPE P50444-B21 is a 16GB single-rank DDR5-4800 ECC Registered DIMM (RDIMM) supplied as an HPE-branded kit for ProLiant Gen11 servers. DDR5-4800 runs at nearly double the base clock rate of DDR4-3200, which translates to measurably higher memory bandwidth on memory-bound workloads — database in-memory caching, virtualization host density, and analytics jobs all benefit from the wider pipe. ECC registration catches and corrects single-bit errors in real time, keeping long-running server processes stable without manual intervention. Single-rank (1Rx8) organization allows more DIMMs per channel before hitting signal-integrity limits, giving you flexibility to populate memory slots incrementally as workload demands grow.

Compatibility

This kit is engineered and validated for HPE ProLiant Gen11 server platforms — including the DL360 Gen11, DL380 Gen11, ML350 Gen11, and other Gen11 tower, rack, and blade systems that support DDR5 RDIMM slots. HPE memory kits are validated against HPE's Active Health System and platform firmware; using non-HPE DIMMs in these systems can trigger memory advisories or reduce supported DIMM configurations. Confirm your specific server's memory population rules in the HPE QuickSpecs for that platform before ordering — slot pairing and channel-fill order affect whether the system runs in optimal dual-channel mode. This DIMM is not cross-compatible with Gen10 or earlier ProLiant systems, which use DDR4.

Installation Notes

Operating temperature range is 5°C to 50°C (41°F to 122°F); storage is rated to -40°C to 85°C. At elevations above 1,524 m (5,000 ft), derate maximum inlet air temperature linearly down to 40°C at 3,048 m (10,000 ft) — relevant for high-altitude data center deployments. Relative humidity must stay non-condensing (5%–95% operating). Standard DIMM installation: power down, ground yourself, align the notch, seat firmly until both retention clips engage. No tools required beyond standard ESD precautions.