HPE
SKU: P25526-B21
Overview
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Overview
Questions about this product? Free pre-sales support from a senior specialist — product questions, compatibility checks, BOM quotes, price confirmation — typically answered within one business day. Need camera placement or system design work? Engineering time is $175 per hour (qty 1 = 1 hour). Hardware buyers get up to one hour ($175) credited back on their order.
The HPE P25527-B21 is a dual-interface adapter card designed specifically for the HPE ProLiant DL385 Gen10 Plus server platform, delivering both NVMe storage connectivity and Ethernet networking from a single expansion slot. Weighing just 0.62 lb, this factory-new adapter targets environments where storage throughput and network integration must coexist in a dense rack footprint — think edge recording nodes, high-transaction database tiers, or surveillance back-end infrastructure where NVMe latency matters.
If you are evaluating HPE server components for a storage-intensive deployment, the P25527-B21 warrants consideration wherever the DL385 Gen10+ is the host platform and both NVMe and Ethernet expansion are needed simultaneously.
The P25527-B21 is validated for the HPE ProLiant DL385 Gen10 Plus. Confirm your chassis generation before ordering — HPE adapter cards are platform-matched and are not guaranteed interchangeable across DL385 generations. For broader server storage adapter options or to compare against other HPE expansion cards, review the full HPE server accessory catalog. UNSPSC commodity code 43201404 classifies this as a network interface card/adapter, consistent with its dual NVMe/Ethernet role.
No additional package contents data is available from current evidence — verify with your order confirmation for mounting hardware or documentation inclusions.
Q: What server platform is the P25527-B21 designed for?
A: The P25527-B21 is designed and validated for the HPE ProLiant DL385 Gen10 Plus server. It is not confirmed compatible with earlier DL385 generations or other HPE server lines without additional HPE validation.
Q: What interfaces does the P25527-B21 provide?
A: The P25527-B21 provides both NVMe and Ethernet interfaces, allowing a single PCIe slot to handle high-speed storage connectivity and network I/O simultaneously.
Q: Is the P25527-B21 (also searched as P25527 B21) a new or refurbished unit?
A: Units sourced through standard distribution channels are factory-new. Confirm condition at time of order if provenance is critical to your procurement process.
Q: What does the 12GB designation in the product name refer to?
A: The 12GB designation in the HPE product name refers to the adapter's interface bandwidth specification. Confirm the exact throughput ceiling with HPE's official product documentation for your specific workload planning.
Q: Where is the P25527-B21 manufactured?
A: HPE lists multiple countries of origin for this part: China (CN), Czech Republic (CZ), Japan (JP), Mexico (MX), and Singapore (SG), reflecting HPE's global manufacturing footprint for server components.

The P25527-B21 is one of those platform-specific adapter cards that saves real rack space when you're building out a DL385 Gen10 Plus node and need both NVMe storage bandwidth and Ethernet connectivity without burning two PCIe slots. At 0.62 lb, it's clearly a low-profile form factor — that matters in a fully populated 2U chassis where neighboring cards and cable routing leave little room for a full-height double-wide card.
Technical Highlights:
Deployment Considerations:
Best fit: a DL385 Gen10 Plus node serving as a high-ingest storage tier in a video surveillance back-end or edge analytics rack, where NVMe throughput and Ethernet connectivity both need to land in a single expansion slot without a second card occupying space you don't have.
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