HPE DL385 GEN10+ 12GB NVME 1P Adptr - P25526-B21

HPE P25526-B21 12Gb NVMe and Ethernet Adapter for ProLiant DL385 Gen10+

The HPE P25526-B21 is a dual-interface adapter — combining NVMe and Ethernet connectivity — designed for the HPE ProLiant DL385 Gen10+ server platform. If you're expanding storage bandwidth or adding a network path to a DL385 Gen10+ deployment, this is the purpose-built option for that chassis. The P25526-B21 (often searched as P25526 B21) ships at 0.45 lb, so it adds negligible weight to a rack configuration.

Key Features

• NVMe Interface: NVMe operates over PCIe rather than legacy SATA/SAS pathways, which means significantly lower latency and higher throughput for storage-intensive workloads — relevant if you're running video management databases, surveillance archives, or analytics pipelines on the DL385 Gen10+.
• Ethernet Interface: The onboard Ethernet capability means the card handles both storage and network traffic, reducing the number of discrete adapters you need to slot and manage in a dense server build.
• Platform-Specific Fit: Designed for the DL385 Gen10+, this adapter is validated against HPE's firmware and driver stack for that chassis — reduces integration risk compared to third-party alternatives that may require manual driver management or lack iLO visibility.
• Compact Form Factor: At 0.45 lb, installation is straightforward and does not add thermal or structural stress to the chassis.

Integration and Compatibility

The P25526-B21 is intended for the HPE ProLiant DL385 Gen10+ platform. Verify slot availability and firmware revision on your target chassis before ordering. UNSPSC classification 43201500 (computer storage devices and media) confirms this is a hardware component, not a software or service SKU. For broader HPE server and storage solutions, review the full HPE catalog for compatible accessories and expansion options. If you're architecting a network video recorder or surveillance server build on HPE hardware, pairing the right storage adapter at spec time avoids costly retrofits later. Consult your PoE switch and network topology plans alongside server adapter selection to ensure end-to-end bandwidth alignment.

Frequently Asked Questions

Q: What server platform is the P25526-B21 designed for?

A: The P25526-B21 is designed for the HPE ProLiant DL385 Gen10+ server platform.

Q: What interfaces does the P25526-B21 provide?

A: It provides both NVMe and Ethernet interfaces, combining storage and network connectivity in a single adapter.

Q: How much does the P25526-B21 weigh?

A: 0.45 lb — a lightweight add-in card that won't add meaningful thermal or structural load to the chassis.

Q: Where is the P25526-B21 manufactured?

A: Country of origin is China (CN), per distribution data.

Q: Is the P25526-B21 compatible with other HPE server generations?

A: Available evidence specifies the DL385 Gen10+ as the target platform. Compatibility with other generations is not confirmed in the available documentation — verify with HPE before deploying in a different chassis.

James Everett

The P25526-B21 is a purpose-fit adapter for the DL385 Gen10+ — the dual NVMe and Ethernet interface combination on a single card is the practical detail worth noting when you're spec'ing out a server that needs both storage bandwidth and network connectivity without consuming two PCIe slots.

Technical Highlights:

• NVMe + Ethernet in One Card: Reduces slot consumption in the DL385 Gen10+ chassis — relevant when you're balancing GPU, storage, and network expansion in a high-density build.
• Platform-Validated Design: Purpose-built for the DL385 Gen10+, meaning HPE's iLO management stack and firmware update path cover this adapter — no manual driver sourcing required.
• 0.45 lb Form Factor: Light enough that chassis airflow and slot stress are non-issues during installation.

Deployment Considerations:

• Confirm available PCIe slot type and count on your specific DL385 Gen10+ configuration before procurement — Gen10+ variants differ in riser options.
• Evidence covers interface type and platform target only; lane count, port speed, and driver version requirements are not confirmed here — pull the HPE QuickSpecs for P25526-B21 before finalizing a storage architecture decision.

Best fit for a DL385 Gen10+ deployment where you need to consolidate NVMe storage access and a dedicated Ethernet path onto a single adapter — particularly relevant in surveillance server builds where storage I/O and network throughput run concurrently under sustained load.