HPE DL380 GEN10 5118 64G 8SFF Reman SVR - P06422R-B21

HPE P06422R-B21 DL380 Gen10 Remanufactured 2U Rack Server

Overview

The HPE P06422R-B21 is a remanufactured DL380 Gen10 2U rack server configured with an Intel Xeon Gold 5118 processor, 64GB of RAM, and an 8x Small Form Factor (SFF) drive bay chassis. The 'R' suffix in the part number designates HPE's factory remanufactured program — these units are refurbished to HPE's production standards, making the P06422R-B21 a cost-conscious path to proven Gen10 compute without sourcing grey-market hardware. If you're expanding an existing DL380 Gen10 environment or standing up a secondary workload tier, this configuration covers mid-range compute density in a standard 2U footprint.

Key Features

• Intel Xeon Gold 5118 (12C/24T): A 12-core processor well-suited to parallel workloads — VMS recording servers, database backends, and virtualization hosts where thread count matters more than raw single-core clock speed.
• 64GB DDR4 RAM: Enough headroom to run a moderately sized hypervisor stack or a multi-channel video management application without immediate memory expansion. If your workload grows, the DL380 Gen10 platform supports significant additional DIMM capacity.
• 8x SFF Drive Bays: Small Form Factor bays accept 2.5-inch SAS/SATA/NVMe drives depending on backplane configuration — giving you flexibility to configure RAID arrays for either performance or redundancy depending on the application.
• 2U Rack Form Factor (74.93 x 44.45 x 8.89 in): Standard 2U height fits into any EIA-standard rack. At 20.41 lb, it's manageable for a one- or two-person rack installation without lift equipment in most data center environments.
• HPE Remanufactured Program: Factory remanufactured units go through HPE's production-standard refurbishment process — a meaningful distinction from aftermarket refurbishers. This is genuine HPE hardware, not a third-party rebuild.

Integration and Compatibility

The DL380 Gen10 platform integrates with HPE iLO (Integrated Lights-Out) management, HPE OneView, and is broadly compatible with VMware vSphere, Microsoft Hyper-V, and Red Hat Enterprise Linux workloads. As a Gen10 platform, it supports HPE's Persistent Memory (NVDIMM) and NVMe drive options depending on how the backplane and riser cards are configured. Verify your specific backplane and riser configuration before ordering drives or expansion cards — the P06422R-B21 (often searched as P06422R B21) base config may differ from a new-build CTO unit.

Frequently Asked Questions

Q: What does the 'R' suffix mean in P06422R-B21?

A: The 'R' designates HPE's factory remanufactured program. These are HPE-refurbished units brought back to production standards — not third-party rebuilt servers. It is a cost-effective way to deploy genuine HPE Gen10 hardware.

Q: What processor is included in the P06422R-B21?

A: The product name specifies an Intel Xeon Gold 5118, a 12-core processor from Intel's Skylake-SP generation supported by the DL380 Gen10 platform.

Q: How many drive bays does the P06422R-B21 have?

A: The configuration includes 8 Small Form Factor (SFF) drive bays, which accept 2.5-inch drives. Supported drive types (SAS, SATA, NVMe) depend on the backplane configuration.

Q: What are the physical dimensions and weight of the P06422R-B21?

A: The server measures 74.93 x 44.45 x 8.89 inches (L x W x H) and weighs 20.41 lb, fitting a standard 2U rack slot.

Q: Is the P06422R-B21 compatible with HPE iLO management?

A: Yes, the DL380 Gen10 platform includes HPE iLO (Integrated Lights-Out) for out-of-band server management, consistent with the broader Gen10 server family.

Karl Wilson

The P06422R-B21 is the remanufactured variant of HPE's DL380 Gen10 in the 5118/64G/8SFF configuration — a platform I've deployed repeatedly as a mid-tier VMS recording server and virtualization host where the budget doesn't justify new-iron pricing but the workload still demands enterprise-grade reliability. The 20.41 lb chassis in a 2U slot is dense enough to keep your rack count low without the thermal challenges of blade form factors.

Technical Highlights:

• Xeon Gold 5118 (12C): Twelve cores handle concurrent camera decode, analytics processing, and storage I/O simultaneously — a single-socket config that covers most mid-scale VMS deployments without the complexity of dual-socket licensing.
• 64GB DDR4 baseline: Sufficient for a VMware ESXi host running two or three VMs — a recorder, a management server, and a lightweight analytics node — before you start feeling memory pressure.
• 8x SFF bay chassis: Eight 2.5-inch bays give you enough raw slot count to build a RAID 6 array with a hot spare, which is the minimum I'd recommend for any always-on surveillance storage application.

Deployment Considerations:

• Verify the exact backplane and riser card configuration on your unit before ordering drives or PCIe expansion cards — remanufactured units may ship with varying backplane options that affect NVMe support.
• The 'R' (remanufactured) designation means HPE warranty terms differ from new-unit P06422-B21 purchases — confirm the warranty coverage in your quote before committing to a multi-year deployment.

Best fit: a secondary recording tier or edge compute node in a distributed physical security deployment where you need proven Gen10 compute at a reduced acquisition cost and your rack already runs HPE infrastructure.