HPE INT Xeon-g 5415+ CPU for HPE OEM - P61443-B21
High-performance Xeon-G 5415+ processor engineered for HPE server systems where data-intensive workloads and mission-critical applications demand
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The P49597-B21 is HPE's factory-packaged Intel Xeon Gold 5415+ processor option kit for ProLiant Gen11 servers — an eight-core, 2.9GHz Sapphire Rapids CPU suited to workloads that need a balanced mix of single-thread performance and multi-core throughput without pushing into the higher TDP tiers. If you're expanding compute capacity in a HPE ProLiant G11 server and don't need the full core count of the higher-bin Xeon Gold or Xeon Platinum options, the 5415+ delivers a practical performance-per-watt tradeoff at 150W TDP. The kit ships sealed in static-safe packaging with the component processor (P60426-001) and is designed to slot into HPE's validated G11 platform — no compatibility guesswork with third-party parts.
The P49597-B21 (often searched as P49597 B21) is validated for the following HPE ProLiant Gen11 server platforms:
Before ordering, cross-reference your server's QuickSpecs document to confirm the maximum supported processor count, memory configuration rules (DDR5 population order may change with a second CPU installed), and any BIOS version prerequisites for Sapphire Rapids support. HPE typically requires a minimum system ROM version for new processor families — check HPE's Support Center for the applicable advisory for your specific server model. The component part number P60426-001 is the actual processor unit; P49597-B21 is the option kit PN used for ordering and is the reference you'll cite in purchase orders and asset tracking. Both are the same physical unit — one is the kit identifier, one is the component identifier.
For enterprises running network video recorders or server-based VMS platforms on ProLiant hardware, the DL360 Gen11 and DL380 Gen11 are common deployment targets. The 5415+ handles concurrent workloads (recording, analytics, and client streams simultaneously) without the overhead of higher-TDP 12- or 16-core options that may be unnecessary for mid-scale camera counts.
Q: Which HPE ProLiant Gen11 servers are compatible with the P49597-B21?
A: The P49597-B21 is validated for the HPE ProLiant ML110 Gen11, ML350 Gen11, DL110 Gen11, DL320 Gen11, DL360 Gen11, and DL380 Gen11. Always verify against your specific server's QuickSpecs before ordering.
Q: Will the P49597-B21 work in a Gen10 or Gen10 Plus HPE ProLiant server?
A: No. The Xeon Gold 5415+ uses the LGA4677 socket, which is specific to Gen11 (Sapphire Rapids) platforms. It is not physically or electrically compatible with Gen10 or Gen10 Plus servers, which use earlier Intel Xeon Scalable sockets.
Q: What is the warranty on the P49597-B21?
A: The P49597-B21 carries a 3-year manufacturer warranty.
Q: Does the P49597-B21 kit include a heatsink or thermal solution?
A: Based on available evidence, the kit includes the processor unit (component part P60426-001) sealed in a static bag. HPE's Gen11 platforms typically require a separate heatsink option depending on chassis and configuration — verify your server's thermal kit requirements via HPE's QuickSpecs for your specific model.
Q: What is the difference between part number P49597-B21 and P60426-001?
A: P49597-B21 is the HPE option kit part number used for procurement and ordering. P60426-001 is the component (processor unit) part number. The kit contains the single processor unit; both numbers refer to the same physical product at different levels of HPE's part numbering hierarchy.
Q: How many of these processors does a dual-socket DL380 Gen11 require?
A: The P49597-B21 kit includes one processor. A dual-socket deployment requires two kits. Single-socket configurations (such as the DL320 Gen11) require only one kit.

The P49597-B21 is a deliberate mid-tier pick in the Gen11 Xeon Gold lineup — the 5415+'s 150W TDP and 2.9GHz base clock make it the right call when you need per-core throughput without committing to the power and cooling overhead of a 16- or 24-core option. I see this processor specified most often in 1U and 2U ProLiant DL360/DL380 Gen11 builds where the workload is latency-sensitive rather than massively parallel.
Technical Highlights:
Deployment Considerations:
Best fit: a ProLiant DL360 Gen11 or DL380 Gen11 running a VMS platform, database engine, or analytics workload at mid-scale — where 8 fast cores outperform 16 slower ones and where staying under 150W per socket keeps the rack power budget manageable.
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