HPE
SKU: P57855-B21
Overview
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Overview
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The HPE P57854-B21 is the factory-designated NVMe signal cable connecting the second 8-small-form-factor (8SFF) drive box to the system board in an HPE ProLiant DL385 Gen11 server. If you are expanding storage or replacing a failed cable in Box 2 of a DL385 Gen11, this is the correct part — using a generic or mismatched cable in a direct-attach NVMe topology risks degraded signal integrity and loss of drive enumeration. The P57854-B21 (often searched as P57854 B21) is factory-new and genuine HPE, sourced through established distribution channels with no grey-market or parallel-import exposure.
The P57854-B21 is designed exclusively for the HPE ProLiant DL385 Gen11 platform in the 8SFF drive bay configuration. It is not interchangeable with DL380 Gen10/Gen11 or DL385 Gen10 cables — chassis routing, connector keying, and validated signal length differ by generation and model. Before ordering, confirm your chassis is a DL385 Gen11 and that the replacement targets Box 2 specifically. For Box 1 NVMe cabling or SAS/SATA backplane cables on the same platform, consult the HPE server accessories catalog for the correct companion SKUs. If you are planning a full NVMe storage upgrade across multiple DL385 Gen11 nodes, verify drive bay population rules in the HPE QuickSpecs before ordering cable quantities.
Q: What server platform is the P57854-B21 designed for?
A: The P57854-B21 is designed specifically for the HPE ProLiant DL385 Gen11 server in the 8SFF drive bay configuration, targeting Box 2.
Q: Is this a NVMe or SAS cable?
A: This is an NVMe direct-attach cable, as indicated by the NVMe interface designation in HPE's product specifications. It is not a SAS or SATA cable.
Q: Can the P57854-B21 be used in a DL385 Gen10 or DL380 Gen11?
A: No. This cable is validated for the DL385 Gen11 only. Connector keying, cable length, and routing are platform-specific. Using it in a different generation or model is not supported.
Q: What does Box 2 refer to in the DL385 Gen11?
A: In HPE's DL385 Gen11 drive bay nomenclature, Box 2 refers to the second drive cage assembly. The P57854-B21 connects that cage's NVMe backplane to the system board.
Q: How much does the P57854-B21 weigh?
A: The cable assembly weighs 0.20 lb, consistent with a signal cable rather than a backplane or structural component.

The P57854-B21 is one of those parts that looks trivial until a DL385 Gen11 node goes into a drive enumeration fault mid-shift. As a direct-attach NVMe cable for Box 2 of the 8SFF configuration, it sits in the critical signal path between your drives and the CPU — the 0.20 lb assembly weight tells you this is a signal cable, not a passive backplane, and HPE validates these at the platform level for a reason.
Technical Highlights:
Deployment Considerations:
This cable belongs in the spares kit for any data center running DL385 Gen11 nodes at scale — a $30–50 part that gates a full node's Box 2 storage capacity is worth stocking before you need it at 2 AM.
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