HPE
SKU: P61220-B21
Overview
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Overview
Questions about this product? Free pre-sales support from a senior specialist — product questions, compatibility checks, BOM quotes, price confirmation — typically answered within one business day. Need camera placement or system design work? Engineering time is $175 per hour (qty 1 = 1 hour). Hardware buyers get up to one hour ($175) credited back on their order.
The HPE P52749-B21 is a 2SFF x4 NVMe U.2/U.3 backplane cage designed specifically for the HPE ProLiant DL320 Gen11 server platform. If you are expanding NVMe storage capacity in a DL320 Gen11 — whether for a high-throughput network video recorder backend, edge AI inference node, or dense data storage application — this cage provides the physical and electrical infrastructure to seat and connect up to two 2.5-inch small form-factor NVMe drives via U.2 or U.3 interfaces.
U.2 and U.3 both use the same SFF-8639 connector, but U.3 extends the spec to support multi-protocol operation (NVMe, SAS, SATA over one port), giving you flexibility to mix drive types as your storage architecture evolves — a meaningful consideration when planning tiered storage for video surveillance workloads or AI compute pipelines that require both fast cache and bulk capacity. This cage is sold as a server storage component and is specific to the DL320 Gen11 chassis — confirm your server's generation and bay configuration before ordering, as HPE drive cage assemblies are not cross-generation compatible.
This cage is designed exclusively for the HPE ProLiant DL320 Gen11 1U platform. It is not compatible with DL320 Gen10 or earlier chassis, nor with other ProLiant family members (DL360, DL380, etc.) — HPE's backplane form factors and mid-plane connector positions differ between models and generations. Verify your server's existing bay population and the specific cage slot position (front vs. secondary) against HPE's DL320 Gen11 QuickSpecs before ordering. Pair with U.2 or U.3 NVMe SSDs sourced from HPE's supported drive list to ensure full firmware compatibility and Smart Array/controller integration.
Q: What server is the P52749-B21 compatible with?
A: The P52749-B21 is designed specifically for the HPE ProLiant DL320 Gen11 server. It is not cross-compatible with earlier DL320 generations or other ProLiant models.
Q: Does the P52749-B21 support both U.2 and U.3 NVMe drives?
A: Yes. The cage supports both U.2 and U.3 NVMe drives via the SFF-8639 connector standard. U.3 additionally supports multi-protocol operation for mixed drive environments.
Q: How many drives does this cage support?
A: The 2SFF designation indicates two 2.5-inch small form-factor drive bays per cage assembly.
Q: Is this a hot-plug capable backplane?
A: Hot-plug capability depends on the server platform configuration and firmware. Verify hot-plug support against HPE's DL320 Gen11 QuickSpecs and your specific storage controller before assuming hot-swap operation in a live environment.
Q: Where is the P52749-B21 manufactured?
A: Country of origin is CN (China), consistent with HPE's standard ProLiant server component manufacturing.

The P52749-B21 is a platform-locked component — its value is entirely in what it unlocks for the DL320 Gen11 chassis. If you are building out NVMe storage density in a 1U footprint for a surveillance recording backend or edge compute node, the x4 lane-per-drive allocation is the spec that matters most: you are not sharing bandwidth across drives on a bifurcated bus, which keeps per-drive latency predictable under concurrent read/write from multiple camera streams or inference pipelines.
Technical Highlights:
Deployment Considerations:
Best fit for integrators building dense 1U NVMe storage nodes inside the DL320 Gen11 — specifically where a surveillance recording server or edge AI appliance needs additional fast-tier drive bays without migrating to a larger chassis form factor.
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