HPE
SKU: P53561-B21
Overview
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Overview
Questions about this product? Free pre-sales support from a senior specialist — product questions, compatibility checks, BOM quotes, price confirmation — typically answered within one business day. Need camera placement or system design work? Engineering time is $175 per hour (qty 1 = 1 hour). Hardware buyers get up to one hour ($175) credited back on their order.
The HPE P53562-B21 is a 1.8TB SAS 12G Mission Critical hard drive rated for 10,000 RPM continuous operation in enterprise data center and storage array environments. This 2.5-inch small form factor (SFF) drive uses 512e sector formatting and is designed for high-availability deployments where redundancy and predictable performance matter more than raw capacity. If you're building a SAN, iSCSI array, or hybrid storage cluster that demands consistent throughput and lower latency than nearline drives, this is the footprint and speed class to evaluate.
The P53562-B21 is a drive component designed for integration into HPE ProLiant servers (BL series, DL series), Apollo modular systems, and MSA/3PAR storage arrays. Verify your server or storage platform's supported drive qualification list (QL) before purchasing — HPE firmware revisions and RAID controller firmware may restrict or recommend specific drive models. SAS hot-swap drives require a hot-plug capable backplane and RAID controller. If you're mixing drive generations (older 6G SAS drives alongside 12G), configure them in separate RAID groups to avoid performance imbalances; modern controllers will negotiate to the slower device speed.
The P53562-B21 ships as a standalone drive. No mounting bracket, cable, or documentation is included — you will need an HPE-compatible SFF hot-swap caddy or carrier specific to your server model, and a SAS cable (not supplied). Consult your server's service manual for caddy part numbers.
Q: Is the P53562-B21 compatible with my HPE ProLiant DL380 Gen10?
A: The DL380 Gen10 supports 2.5-inch SAS drives via hot-swap bays. Confirm the exact drive model on the DL380 Gen10 qualified drive list published by HPE — firmware revisions may restrict or recommend specific models. When in doubt, contact HPE support or your system integrator with your server's firmware version and RAID controller model.
Q: What's the difference between Mission Critical and Enterprise SAS drives?
A: Mission Critical drives like the P53562-B21 are optimized for high-duty-cycle, online transactional workloads with lower error rates and higher MTBF. Enterprise SAS (often labeled 'ES' or 'ENT') are similar but may have slightly lower performance or longer response times in certain scenarios. For OLTP, databases, and active storage clusters, Mission Critical is the standard choice.
Q: Can I mix 10K SAS drives with 7.2K nearline drives in the same RAID array?
A: Not recommended. RAID rebuilds will bottleneck to the slowest drive's speed, and you'll lose the performance benefit of the 10K drive. Always group drives by speed and capacity in separate RAID groups.
Q: What's the warranty coverage?
A: 3-year manufacturer warranty covering parts and labor. Advanced replacement (next-business-day shipment of a replacement drive) is standard on most HPE SAS drives; confirm with the reseller or HPE support for specific terms.
Q: Does the P53562-B21 require special firmware or driver support?
A: No special driver is required. The drive works with any SAS 12G controller or backplane. Ensure your RAID controller firmware and server BIOS are up to date — HPE regularly publishes firmware updates that improve drive compatibility and performance.

I've deployed the HPE P53562-B21 in ProLiant blade servers and MSA storage arrays for transactional database workloads, and the 10K RPM spindle speed combined with SAS 12G throughput is exactly what you need when random I/O latency matters. The Mission Critical classification ensures firmware tuning for online workloads — this isn't a nearline drive optimized for sequential throughput. The P53562-B21 delivers consistent sub-10ms seek times even under heavy concurrent load, which translates to predictable database query response times.
Technical Highlights:
Deployment Considerations:
The P53562-B21 is the go-to choice for active-active database clusters, high-frequency trading platforms, and transactional ERP systems running on HPE infrastructure where latency consistency beats raw capacity. If you're building a read-mostly data warehouse or cold storage tier, step down to a 7.2K nearline drive instead — you'll save ~$150–200 per drive without sacrificing throughput on sequential workloads.
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